Marvin A. Kaplan, M.D., F.A.C.P.; David P. Parker, M.D., (Associate); John E. Connolly, M.D.
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Seventeen patients presenting clinically with aortic valvular stenosis were challenged at cardiac catheterization with isoproterenol, and premature beats were intentionally elicited; 10 of these had coexistent aortic valvular stenosis and functional subaortic stenosis. Isoproterenol tests were done because of the death of a patient of low cardiac output after aortic valve replacement. At termination of cardiopulmonary bypass it was noted that the vigorous-appearing cardiac contractions were inadequate to open the ball valve. Postmortem study showed valvular calcification and concomitant subvalvular muscular hypertrophy, especially involving the interventricular septum.
All 10 patients appeared clinically to have valvular stenosis alone as evidenced by
Kaplan MA, Parker DP, Connolly JE. Concomitant Aortic Valvular and Functional Subaortic Stenosis.. Ann Intern Med. 1970;72:784. doi: https://doi.org/10.7326/0003-4819-72-5-784_2
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Published: Ann Intern Med. 1970;72(5):784.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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