Patricia A. McIntyre, M.D., F.A.C.P.; Monica B. Spaulding, M.D.; Pablo Dibos, M.D.; Henry N. Wagner Jr., M.D., F.A.C.P.
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Radioactive colloids have been used for several years as liver scanning agents. Although the major proportion of the injected colloid localizes in the reticuloendothelial (RE) cells of the liver, smaller but significant amounts are cleared by the RE cells of the spleen and bone marrow. This study was undertaken to evaluate the usefulness of imaging the distribution of radioactive colloids in the spleen and bone marrow, together with the liver. Spleen scans obtained with technetium-99m sulfur colloid were found to be useful in detecting splenomegaly, focal lesions of the spleen, and decreased function of the RE system of the spleen.
McIntyre PA, Spaulding MB, Dibos P, Wagner HN. Clinical Usefulness of Imaging the Distribution of the Reticuloendothelial System.. Ann Intern Med. ;72:794–795. doi: 10.7326/0003-4819-72-5-794_4
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Published: Ann Intern Med. 1970;72(5):794-795.
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