Louise Riff, M.D.; Vera Olexy, B.S.; George Gee Jackson, M.D., F.A.C.P.
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Infection with Gram-negative bacilli is a problem of increasing frequency and importance. Often the strains causing these infections are resistant to available antibiotics. Gentamicin is an aminoglycoside antibiotic effective against most species of Gram-negative bacilli. We have used it in the treatment of 150 patients with life-threatening or serious Gram-negative bacillary infections. Most of the infections were hospital-acquired; one third of the patients had underlying diseases sufficiently serious to be designated as rapidly or ultimately fatal. Bacteremia from various sources and pyelonephritis accounted for more than two thirds of the diagnoses; endocarditis, pneumonia, and meningtis were prominent among the remainder.
Riff L, Olexy V, Jackson GG. Gentamicin Treatment of Serious Gram-Negative Bacillary Infections.. Ann Intern Med. 1970;72:797. doi: https://doi.org/10.7326/0003-4819-72-5-797_1
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Published: Ann Intern Med. 1970;72(5):797.
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