Kenrad E. Nelson, M.D.; Stuart A. Levin, M.D.; Mark H. Lepper, M.D., F.A.C.P.; Harold W. Spies, M.D.; Ruth Lawrence, M.D.
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The course and outcome of 1,073 cases of bacterial meningitis treated in the interval from 1954 to 1965 were reviewed in order to [a] compare the efficacy of tetracycline and chloromycetin in the treatment of H-influenza meningitis and of sulfadiazine chloromycetin and penicillin in meningococcal meningitis in alternate case studies, [b] determine the effect on the course and outcome of bacterial meningitis of suboptimal therapy received prior to hospitalization, and [c] examine secular changes in morbidity and mortality.
Of the 196 H-influenza meningitis patients treated with tetracycline, 7 (3.6%) died; 10 (6.5%) of 153 patients treated with chloromycetin died (P
Nelson KE, Levin SA, Lepper MH, et al. Bacterial Meningitis: A Review of 1,073 Cases.. Ann Intern Med. 1970;72:798. doi: https://doi.org/10.7326/0003-4819-72-5-798_1
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Published: Ann Intern Med. 1970;72(5):798.
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