J. Stauffer Lehman Jr., M.D.; Zoheir Farid, M.D.; Samir Bassily, M.D.; Donald C. Kent, M.D., F.A.C.P.
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Obstructive urinary tract disease due to Schistosoma haematobium infection was evaluated as a model of hydronephrosis in man. The effect of hydronephrosis and bacteriuria on renal function was studied. Maximal urinary concentrating ability (Umax); 24-hr creatinine clearance, and intravenous urography were tested before and after treatment in 35 men, aged 4 to 52 years, with urinary schistosomiasis. Nine patients had minimal urographic abnormalities and were able to concentrate (mean = 862 mOsm/kg) better (P < 0.0005) than 12 patients with bilateral obstructive uropathy (763 mOsm/kg). In eight patients with bilateral obstructive uropathy and bacterial urinary tract infection Umax (583 mOsm/kg)
Lehman JS, Farid Z, Bassily S, et al. Maximal Urine Concentration in Hydronephrosis (Due to Urinary Schistosomiasis) With and Without Bacteriuria.. Ann Intern Med. 1970;72:802. doi: https://doi.org/10.7326/0003-4819-72-5-802_2
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Published: Ann Intern Med. 1970;72(5):802.
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