William G. Bouman, M.D.; John M. Weller, M.D., F.A.C.P.
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Sixty-six consecutive adult patients having the nephrotic syndrome were studied to determine the relationship between various clinical factors (age, sex, hypertension, hematuria, reduced glomerular filtration rate, and proteinuria) and the type of histological alteration found on percutaneous renal biopsy.
The commoner histological diagnoses were membranous glomerulonephritis (33%), proliferative glomerulonephritis (20%), membranous and proliferative glomerulonephritis (10%), lupus nephritis (10%), and normal kidney (10%). No correlation was found between age, sex, level of blood pressure, degree of hematuria or proteinuria, or reduction in glomerular filtration rate, and the type of histological alteration.
These clinical factors cannot be used to predict the type
Bouman WG, Weller JM. The Nephrotic Syndrome in the Adult: Relationship of Clinical and Histological Findings.. Ann Intern Med. 1970;72:803. doi: https://doi.org/10.7326/0003-4819-72-5-803_2
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Published: Ann Intern Med. 1970;72(5):803.
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