Kenneth D. Gardner Jr., M.D., (Associate)
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Cystic disease of the renal medulla is a devastating illness, affecting primarily young adults and carrying a 100% chance of absolute renal failure. The late azotemic phase of the disease is characterized by a defect in urinary concentrating ability, renal sodium wasting, and cystic destruction of the inner kidney. The clinical characteristics of the latent and early azotemic phases of the disease have not been defined, even though they constitute a necessary prerequisite for the effective application of therapy. To define the clinical signs that characterize the latent and early azotemic stages, 13 subjects who are members of two kindreds
Gardner KD. The Evolution of Clinical Signs in Cystic Disease of the Renal Medulla.. Ann Intern Med. 1970;72:804. doi: 10.7326/0003-4819-72-5-804_1
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Published: Ann Intern Med. 1970;72(5):804.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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