REX N. MACALPIN, M.D.; EDWIN G. ZALIS, M.D.; CHARLES F. KIVOWITZ, M.D.
A patient with coronary artery disease had at least 77 episodes of ventricular tachycardia over a 4-year period, all of which required electroconversion. The usual therapies, including atrial pacing, failed to prevent recurrences that were increasingly frequent. The initiation of therapy with bretylium tosylate abruptly terminated the recurrences of arrhythmia, and the patient has had no episodes for 20 months while taking 400 mg, by mouth, every 8 hr.
MACALPIN RN, ZALIS EG, KIVOWITZ CF. Prevention of Recurrent Ventricular Tachycardia with Oral Bretylium Tosylate. Ann Intern Med. 1970;72:909–912. doi: 10.7326/0003-4819-72-6-909
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Published: Ann Intern Med. 1970;72(6):909-912.
Cardiology, Rhythm Disorders and Devices.
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