ROBERTO FRANCO-SAENZ, M.D.; GEORGE D. LUDWIG, M.D., F.A.C.P.; LEE W. HENDERSON, M.D., F.A.C.P.
One of the rarest manifestations of sarcoidosis is involvement of the skull; only five cases have been reported (1-5). Bone lesions of any type are rare, and osseous localization is usually more frequent in the chronic stage, especially when there is simultaneous cutaneous involvement (6, 7). A young man with apparent hyperparathyroidism or hypervitaminosis D proved to have sarcoidosis with noncaseating granulomas in a liver and kidney biopsy. Roentgenograms of the skull showed multiple osteolytic lesions, biopsy of which showed scattered noncaseating granulomas consistent with sarcoidosis.
FRANCO-SAENZ R, LUDWIG GD, HENDERSON LW. Sarcoidosis of the Skull. Ann Intern Med. 1970;72:929–931. doi: 10.7326/0003-4819-72-6-929
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Published: Ann Intern Med. 1970;72(6):929-931.
Emergency Medicine, Endocrine and Metabolism, Gastroenterology/Hepatology, Liver Disease, Parathyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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