GERALD L. BAUM, M.D., F.A.C.P.; PHILLIP I. LERNER, M.D.
A 36-year-old laboratory worker exposed to a culture of Blastomyces dermatitidis developed primary pulmonary blastomycosis. The X-ray progression of the lesion is classic for primary pulmonary infections in general, with enlargement of a right hilar node and its subsequent return to normal size. The organism was cultured from the patient's sputum when the lymph node was enlarged. Serologic studies for blastomycosis were negative both in the patient and in his co-workers who were similarly exposed to this culture. This case represents the first clinically documented observation of primary pulmonary infection with B. dermatitidis and supports the theory that the pathogenesis of almost all cases of this disease, regardless of their manifestations, is by way of primary pulmonary infection.
BAUM GL, LERNER PI. Primary Pulmonary Blastomycosis: A Laboratory-Acquired Infection. Ann Intern Med. 1970;73:263–265. doi: https://doi.org/10.7326/0003-4819-73-2-263
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Published: Ann Intern Med. 1970;73(2):263-265.
Infectious Disease, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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