NICHOLAS P. CHRISTY, M.D., F.A.C.P.
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To the editor: I read with interest the paper "The 48-Hour Adrenocorticotrophin Infusion Test for Adrenocortical Insufficiency" by Rose and associates (1) in the July 1970 ANNALS. The authors believe that this test, which entails a 3-day admission, is advantageous because it distinguishes among normal subjects, patients with secondary, and patients with primary adrenocortical insufficiency, whereas more rapid methods, described in the years 1965 to 1967 and cited by Rose and colleagues as their references (3-5), occasionally failed to make that distinction. In two papers published still earlier, in 1955 and 1956, our group showed that the 4-hr intravenous adrenocorticotrophin
CHRISTY NP. ACTH Test for Adrenocortical Insufficiency. Ann Intern Med. ;73:858–859. doi: 10.7326/0003-4819-73-5-858_2
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Published: Ann Intern Med. 1970;73(5):858-859.
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