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Mutation involves first a chemical alteration in DNA structure (premutation) followed by various mechanisms (cellular processes) to correct the change, for example, photo reactivating enzymes, excision repair, and recombination processes. This Ciba Symposium was held in 1969, at the instigation of Dr. C. Auerbach (a participant), to emphasize the role of cellular repair processes. Twelve papers by noted authorities cover a wide range of related subjects: modification of DNA by ultraviolet light, various chemical mutagens, mutagen specificity, ribosome mutations, repair mechanisms, and mutations in mice. Presentation of the papers was followed by recorded discussions. The medical importance of this field
Mutation as Cellular Process.. Ann Intern Med. ;73:878–879. doi: 10.7326/0003-4819-73-5-878_2
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Published: Ann Intern Med. 1970;73(5):878-879.
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