STEPHEN J. LERMAN, M.D.; LINDSEY M. LERMAN, A.B.; GEORGE A. NANKERVIS, Ph.D., M.D.; ELI GOLD, M.D.
The availability of rubella vaccine makes it important to identify the 20% of women in the childbearing age who are susceptible and at risk for rubella during pregnancy. A study of 275 women 15 to 56 years of age (median, 20 years) was undertaken to determine the correlation between history of rubella and presence of antibody. A history of rubella was accompanied by a significant level of antibody in 92% of the subjects, however, over 50% with "no history" of rubella and 85% who were "not sure" had antibody. History was also not a specific indicator of immunity; 7 of 38 susceptible subjects reported past rubella, a false-positive response of 18%. Determination of circulating antibody is the only reliable method for deciding which adult women should receive rubella vaccine.
LERMAN SJ, LERMAN LM, NANKERVIS GA, et al. Accuracy of Rubella History. Ann Intern Med. 1971;74:97–98. doi: https://doi.org/10.7326/0003-4819-74-1-97
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Published: Ann Intern Med. 1971;74(1):97-98.
Infectious Disease, Prevention/Screening.
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