THOMAS M. BUCHANAN, M.D.; GEO. F. BROOKS, M.D.; PHILIP S. BRACHMAN, M.D.
The tularemia skin test is a valuable diagnostic tool for the clinician and the epidemiologist. It is sensitive and specific for tularemia; it becomes positive earlier in the course of illness and is positive longer after infection than the agglutination test. Half of all patients with clinical tularemia are skin-test positive the day they present to the physician. It is a delayed hypersensitivity reaction read after 48 hr and can easily be administered and read at the bedside. It rarely causes a rise in the antibody titer and, once positive, may remain positive for as long as 40 years.
BUCHANAN TM, BROOKS GF, BRACHMAN PS. The Tularemia Skin Test: 325 Skin Tests in 210 Persons: Serologic Correlation and Review of the Literature. Ann Intern Med. ;74:336–343. doi: 10.7326/0003-4819-74-3-336
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Published: Ann Intern Med. 1971;74(3):336-343.
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