PAUL H. SCHREIBMAN, M.D.; LIDIA GORANSKY DE KOLIREN, M.D.; RONALD A. ARKY, M.D.
A patient with hepatic metastases of an insulin-producing islet cell carcinoma has been successfully treated with streptozotocin. At 6 months posttreatment, liver scans demonstrate complete regression of tumor, and blood glucose and insulin levels have returned to normal. The pharmacology of and indications for streptozotocin (a 1-methyl, nitrosourea-glucosamine antitumor antibiotic) are discussed.
SCHREIBMAN PH, DE KOLIREN LG, ARKY RA. Metastatic Insulinoma Treated with Streptozotocin. Ann Intern Med. 1971;74:399–403. doi: 10.7326/0003-4819-74-3-399
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Published: Ann Intern Med. 1971;74(3):399-403.
Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology, Pancreatic Cancer, Pancreatic Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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