RAYMOND E. MOLDOW, M.D.
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To the editor: I read with interest Col. O'Neill Barrett, Jr.'s letter describing the association of monocytosis with solid tumor maligancy (Ann Intern Med 73:991-992, 1970).
Mr. Roger Connelly and I reported a retrospective epidemiological study of 257 randomly selected pancreatic cancer cases occurring in Connecticut over a 7-year period (Gastroenterology 55:677-686, 1968). A WBC count and differential was available in 220 patients. Monocytosis, defined as an absolute count greater than 500/mm3, was observed in 76 (30%) of these patients. Utilizing Col. Barrett's normal distribution figure, this represents more cases than would be expected (53 cases).
Our observations, then, are
MOLDOW RE. Monocytosis in Malignancy. Ann Intern Med. 1971;74:449. doi: 10.7326/0003-4819-74-3-449_2
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Published: Ann Intern Med. 1971;74(3):449.
DOI: 10.7326/0003-4819-74-3-449_2