RAYMOND E. MOLDOW, M.D.
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To the editor: I read with interest Col. O'Neill Barrett, Jr.'s letter describing the association of monocytosis with solid tumor maligancy (Ann Intern Med 73:991-992, 1970).
Mr. Roger Connelly and I reported a retrospective epidemiological study of 257 randomly selected pancreatic cancer cases occurring in Connecticut over a 7-year period (Gastroenterology 55:677-686, 1968). A WBC count and differential was available in 220 patients. Monocytosis, defined as an absolute count greater than 500/mm3, was observed in 76 (30%) of these patients. Utilizing Col. Barrett's normal distribution figure, this represents more cases than would be expected (53 cases).
Our observations, then, are
MOLDOW RE. Monocytosis in Malignancy. Ann Intern Med. ;74:449. doi: 10.7326/0003-4819-74-3-449_2
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Published: Ann Intern Med. 1971;74(3):449.
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