VICTORINO S. T. BARRETO, M.D.
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To the editor: In their interesting and very informative article on acute schistosomiasis mansoni (Ann Intern Med 73:379-385, 1970) Dr. Clark and his associates made some interesting observations on the high levels of alkaline phosphatase present in all their patients. They also comment on the possible usefulness of determinations of this enzyme in chronically infected patients.
While living in a highly endemic area, the Northeast of Brazil, we recently had the opportunity of reviewing 81 cases of hepatosplenic schistosomiasis mansoni and found high serum levels of alkaline phosphatase in half of them, reaching more than 2.5 times the upper limit
BARRETO VST. Alkaline Phosphatase in Schistosomiasis. Ann Intern Med. ;74:450–451. doi: 10.7326/0003-4819-74-3-450_2
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Published: Ann Intern Med. 1971;74(3):450-451.
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