Neil A. Buchbinder, M.D.; William C. Roberts, M.D.
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Of 133 necropsy patients with endocarditis 51 had active infective endocarditis; 26, healed infective endocarditis; 11, active endocarditis at sites of prosthetic cardiac valves; and 45, noninfective thrombotic endocarditis. Of 51 with active infective endocarditis, 28 (55%) occurred on previously normal valves, and 22 of them had conditions that predisposed to infection. Streptococcus was the causative agent in 7, staphylococcus in 16, fungi in 10, and in 7 patients the organism was unknown. Right-sided cardiac valves were involved in 11 patients, and 7 were heroin addicts. Each presented with acute pneumonia that later was found to result from infected emboli.
Buchbinder NA, Roberts WC. Vegetative Endocarditis: Clinicopathologic Studies in 133 Patients.. Ann Intern Med. ;74:818. doi: 10.7326/0003-4819-74-5-818_1
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Published: Ann Intern Med. 1971;74(5):818.
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