Robert D. Leachman, M.D.; Roberto Lufschanowski, M.D.; Dennis V. Cokkinos, M.D.
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This communication reviews our experience with the syndrome of midsystolic clicks and late systolic murmur. Twenty-one such patients were studied. Frequent clinical manifestations included palpitations and chest pain. The electrocardiogram was often abnormal, arrhythmias and "ischemic" changes being the common findings. Hemodynamics at rest were invariably normal with no evidence of significant mitral regurgitation. Coronary arteriograms in 10 patients were normal. The left ventricular angiogram in the anteroposterior projection was always characteristic. The mitral annulus was uniformly dilated, resulting in a left ventricle with the shape of a mushroom. A review of similar cases in the pertinent literature indicates that
Leachman RD, Lufschanowski R, Cokkinos DV. The Midsystolic Click and Late Systolic Murmur. Clinical, Electrocardiographic and Hemodynamic Characteristics.. Ann Intern Med. 1971;74:820. doi: https://doi.org/10.7326/0003-4819-74-5-820_4
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Published: Ann Intern Med. 1971;74(5):820.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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