Robert Miller, M.D.; Fuad S. Ashkar, M.D.
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This study was undertaken to determine if there is a therapeutic advantage in calculating the dosage of 131I by formula or administering instead a fixed dosage of radioactive material. One hundred hyperthyroid patients with either Graves' disease, Plummer's disease, or toxic adenomatous disease were selected. The diagnosis was confirmed by 131I uptake and serum thyroxine (Murphy-Pattee) levels. In 60 patients the dose was calculated by using the formula
The remaining 40 patients all received 5 mc each, regardless of uptake or gland size. All 100 patients were randomly selected into the two groups, and no attempt was made to alter
Miller R, Ashkar FS. A Comparison of 131I Dosage in Hyperthyroid Treatment.. Ann Intern Med. 1971;74:824. doi: 10.7326/0003-4819-74-5-824_2
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Published: Ann Intern Med. 1971;74(5):824.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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