Jerry L. Rosenbaum, M.D., F.A.C.P.; Mark S. Kramer, M.D.; Rasib Raja, M.D.; Christopher Boreyko, M.D.
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A resin hemoperfusion column was evaluated for the treatment of nine patients with profound, life-threatening drug intoxication. The column contained 500 g of an uncharged resin, Amberlite XAD-2. The resin has a crosslinked, polystyrene, macroreticular structure with particular surface attraction for lipid-soluble, large molecular weight substances. In five patients blood was pumped through the resin hemoperfusion column at a flow rate of 200 ml/min for 2 hr; four patients had glutethimide intoxication, and one had butalbital intoxication. In four other patients the bloodflow rate through the column was 300 ml/min for 3 hr; two patients had secobarbital intoxication, one ethchloroynol
Rosenbaum JL, Kramer MS, Raja R, Boreyko C. Resin Hemoperfusion to Treat Drug Intoxication.. Ann Intern Med. ;74:832–833. doi: 10.7326/0003-4819-74-5-832_4
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Published: Ann Intern Med. 1971;74(5):832-833.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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