Raymond L. Sherman; E. Lovell Becker, F.A.C.P.
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Abnormalities of proximal tubular function such as glycosuria, aminoaciduria, and defects in acidification have been described previously in the nephrotic syndrome. In this study proximal tubular function was tested in 22 patients with the nephrotic syndrome by measuring lysozyme and glucose urine to serum concentration ratios. Eight of the patients had renal glycosuria, with urine concentrations ranging from 35 to 186 mg/100 ml at serum values below 135 mg/100 ml. These patients had lysozyme concentrations in the urine above the normal range (greater than 2µ/ml). Four of this group has serum lysozyme concentrations in the normal range (4 to 12
Sherman RL, Becker EL. Proximal Tubular Dysfunction in the Nephrotic Syndrome.. Ann Intern Med. 1971;74:833. doi: https://doi.org/10.7326/0003-4819-74-5-833_1
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Published: Ann Intern Med. 1971;74(5):833.
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