S. Schimpff, M.D.; A. Serpick, M.D., F.A.C.P.; B. Stoler, M.D.; B. Rumack, M.D.; H. Mellin, M.D.; G. Joseph, Ph.D.
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An initial two patients (lymphosarcoma, Burkitt's lymphoma) with varicella-zoster exposed the staff and 91 other patients: 19 exposed patients had Hodgkin's disease; 35 had advanced solid tumor; 13 had acute leukemia; and 23 had other lymphomas, myeloma, or chronic leukemia. No staff member developed varicella-zoster. Of the exposed patients, 26% with Hodgkin's disease. 3% with solid tumor, 8% with acute leukemia, and 4% with other tumors subsequently developed varicella-zoster. Herpes zoster usually appeared from 25 to 30 days after exposure. Varicella-zoster developed in 5 of the 11 (45%) exposed patients with Hodgkin's disease who had received prior radiation therapy (4,000
Schimpff S, Serpick A, Stoler B, et al. Epidemic Varicella-Zoster Infection in Cancer Patients.. Ann Intern Med. 1971;74:837. doi: 10.7326/0003-4819-74-5-837_3
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Published: Ann Intern Med. 1971;74(5):837.
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