James P. Smith Jr., M.D., F.A.C.P.; Corazon Yandoc, M.D.; George A. Falk, M.D.; Jo Ann Perry, B.S.
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Acute respiratory failure in adults with severe thoracic scoliosis is said to be a preterminal event. The following analysis of 13 consecutive cases contradicts this assumption. All patients demonstrated a severe restrictive ventilatory defect (average vital capacity, 39% of predicted). In addition, five patients had evidence of airways obstruction, and six had abnormal steady-state diffusing capacities (average, 49% of predicted). Respiratory failure was precipitated by acute bronchopulmonary infection in seven cases, cor pulmonale in five, and barbiturates in one. Admission arterial blood gases were severely deranged: average arterial PCO2, 66 mm Hg; average pH, 7.31; average arterial oxygen saturation, 54%.
Smith JP, Yandoc C, Falk GA, et al. Acute Respiratory Failure in Scoliosis.. Ann Intern Med. 1971;74:841. doi: https://doi.org/10.7326/0003-4819-74-5-841_1
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Published: Ann Intern Med. 1971;74(5):841.
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