N. M. Simon, M.D., F.A.C.P.; W. J. Werner, M.D.; W. A. Franklin, M.D.; E. V. Potter, M.D.
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Twenty-two patients with lupus erythematosus (LE) nephritis were treated with steroids or a combined steroid-immunosuppressive regimen, or both. On 15 occasions steroids were given alone, usually in doses greater than 40 mg/day of prednisone for prolonged periods; on 10 occasions steroids were combined with azathioprine or chlorambucil in doses of 2 to 3 mg/kg body weight/day or 6 to 8 mg/day, respectively, and were reduced in dosage when active disease was controlled. The duration of observation after treatment ranged from 1 to 101 months, with a median of 14 months. Renal tissue was obtained for light microscopic examination in all
Simon NM, Werner WJ, Franklin WA, et al. Comparison of Steroid and Combined Steroid-lmmunosuppressive Treatment of Lupus Erythematosus Nephritis.. Ann Intern Med. 1971;74:842. doi: https://doi.org/10.7326/0003-4819-74-5-842_3
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Published: Ann Intern Med. 1971;74(5):842.
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