Kenneth R. Wilske, M.D., F.A.C.P.; L. A. Healey, M.D., F.A.C.P.
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Horton described temporal arteritis as a clinical syndrome in 1932 but considered it a benign self-limited illness. Several years later the serious complication of blindness was recognized. Since then, it has been shown that giant cell arteritis is not benign or self-limiting but a potentially lethal disease with involvement of large and medium-sized arteries throughout the body. Vascular occlusion leading to infarction of the brain is the most frequent cause of death, followed by similar lesions of the heart. Prolonged morbidity may result from unrecognized giant cell arteritis presenting as incapacitating proximal muscle pain, severe anemia, fever, or malaise. The
Wilske KR, Healey LA. Giant Cell Arteritis—A Multifaceted Disease of Older People.. Ann Intern Med. 1971;74:842. doi: https://doi.org/10.7326/0003-4819-74-5-842_4
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Published: Ann Intern Med. 1971;74(5):842.
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