DAVID A. CLARK, M.D.; EDWARD B. STINSON, M.D.; RANDALL B. GRIEPP, M.D.; JOHN S. SCHROEDER, M.D.; NORMAN E. SHUMWAY, M.D.; DONALD C. HARRISON, M.D.
Between July 1967 and March 1970 we considered 49 patients with end-stage heart disease for cardiac transplantation. After complete cardiologic evaluation to exclude all patients who could benefit from other modes of therapy, 34 patients were selected as potential recipients. Twenty of these underwent cardiac transplantation; 14 did not. While receiving optimal medical therapy before a donor became available, two of the 14 nontransplanted patients improved significantly and were removed from the waiting list. The other 12 died within 2 to 90 days (average, 28 days) while awaiting a suitable donor. Clinical data on both groups are presented. Actuarial statistics show a survival after cardiac transplantation, in our series, of 55% at 3 months, 43% at 6 months, and 36% at 1 year. Six patients are alive at more than 1 year after transplantation. In a select group of carefully evaluated patients cardiac transplantation appears to prolong life.
CLARK DA, STINSON EB, GRIEPP RB, SCHROEDER JS, SHUMWAY NE, HARRISON DC. Cardiac Transplantation in Man: VI. Prognosis of Patients Selected for Cardiac Transplantation. Ann Intern Med. ;75:15–21. doi: 10.7326/0003-4819-75-1-15
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Published: Ann Intern Med. 1971;75(1):15-21.
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