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The fact that there are antigen-antibody reactions that affect central and peripheral neural tissue is indisputable. The classic experimental model is that of experimental allergic encephalomyelitis. Perhaps the best documented clinical counterparts are the neuropathy and encephalomyelopathy that may occur in association with serum sickness, with horse serum being the offending antigen. This book describes such disorders in modest detail in a chapter on allergic neuropathies and demyelinating diseases. The authors also include a chapter on neurologic reactions to drugs but conclude that most of the reactions are toxic rather than allergic, although the exact mechanism of the toxicity is
Allergy of the Nervous System.. Ann Intern Med. 1971;75:489. doi: https://doi.org/10.7326/0003-4819-75-3-489_1
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Published: Ann Intern Med. 1971;75(3):489.
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