FEREIDOUN AZIZI, M.D.
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To the editor: Adulterant substances used in "street drugs" have been implicated as causes of cardiotoxicity (1), acute intravascular hemolysis (2), and pulmonary angiothrombosis (3). The latter was reinvestigated by Douglas, Kafilmout, and Patt (4) who reported, in the December 1971 issue, the abnormal pulmonary function tests and pathological findings of foreign-body type in the lungs of their addict patients. The role of these substances in the pathogenesis of addict liver disease has not been fully investigated.
As many as 80% of heroine and cocaine addicts have abnormal liver function tests (5, 6), with nonspecific changes in liver structure (7).
AZIZI F. Liver Disease in Addicts. Ann Intern Med. ;76:829–830. doi: 10.7326/0003-4819-76-5-829
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Published: Ann Intern Med. 1972;76(5):829-830.
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