Medhat Girgis, M.D.; Judith Duga, M.D.; Leonard J. Levy, M.D.; Edwin E. Gordon, M.D.
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The accumulation of ketone bodies in the plasma of nondiabetic patients is rarely of sufficient magnitude to result in metabolic acidosis. Five episodes of severe ketoacidosis (mean arterial pH, 7.15; range, 6.96 to 7.29) have been documented in four patients with a history of chronic alcoholism, but without diabetes or a family history of diabetes mellitus. A history of significant alcohol intake accompanied by protracted vomiting for several days prior to hospital admission was elicited in each patient. When first seen, all patients exhibited rapid or Kussmaul respirations without an acetone odor to the breath. In addition to the depressed
Girgis M, Duga J, Levy LJ, et al. Nondiabetic Ketoacidosis: A Complication of Alcoholism.. Ann Intern Med. 1972;76:857–858. doi: https://doi.org/10.7326/0003-4819-76-5-857_5
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Published: Ann Intern Med. 1972;76(5):857-858.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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