John H. Lawrence, M.D., F.A.C.P.
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Pituitary disorders, including acromegaly, Cushing's disease, Nelson's syndrome and chromophobe adenoma, have been treated with 910-Mev alpha particles. By using their special radiobiological properties the known resistance of the pituitary to conventional externally delivered radiations (X or gamma rays) has been overcome, and a sufficiently large amount of energy has been delivered to the hyperplastic or adenomatous pituitary without damaging surrounding vital structures and without entering the cranial cavity. During the past 14 years 153 patients with acromegaly were successfully treated, achieving a relief symptoms and signs and a return to normal of elevated growth hormone levels and of other
Lawrence JH. Heavy Particles in the Treatment of Acromegaly, Cushing's Disease, and Nelson's Syndrome.. Ann Intern Med. 1972;76:859. doi: 10.7326/0003-4819-76-5-859_1
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Published: Ann Intern Med. 1972;76(5):859.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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