Mark I. Feldman, M.D.; Galal El-Said, M.D.; Efrain Garcia, M.D., F.A.C.P.; Robert J. Hall, M.D., F.A.C.P.
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Seventeen patients, 16 women and 1 man, 24 to 66 years old, had early nonejection systolic clicks and presented some features similar to those seen in patients with a mid-late systolic click. All patients were studied by complete clinical evaluation, phonocardiography, coronary cineangiography, and left ventriculography; 14 by exercise electrocardiography, and four had apex cardiograms. Presenting symptoms were chest pain in 16, palpitations in nine, and effort intolerance in five. All had early systolic clicks, and eight had apical systolic murmurs starting after the click. In the phonocardiographs the clicks were of low frequency, 40 to 100 msec from S1,
Feldman MI, El-Said G, Garcia E, et al. Early Nonejection Systolic Clicks: A Variant of the Auscultatory Electrocardiographic Syndrome.. Ann Intern Med. 1972;76:863. doi: https://doi.org/10.7326/0003-4819-76-5-863_3
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Published: Ann Intern Med. 1972;76(5):863.
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