David K. Millward, M.D.; Ernest Craige, M.D.
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An opening snap is thought to be diagnostic of either mitral or tricuspid valve stenosis. A study using the simultaneous graphic recording of mitral valve motion by echocardiography along with the phonocardiogram and the left ventricular apex cardiogram has led to the identification of a mitral-valve-opening snap in each of the following cardiac conditions:  tricuspid atresia with a large atrial septal defect;  idiopathic second- and third-degree heart block;  ventricular septal defect;  mitral regurgitation; and  thyrotoxicosis. In each condition the opening snap occurred 90 to 110 msec after A2 on the phonocardiogram and was found to
Millward DK, Craige E. Echocardiographic Studies to Explain Mitral-Valve-Opening Snaps from Nonstenotic Mitral Valves.. Ann Intern Med. 1972;76:867. doi: https://doi.org/10.7326/0003-4819-76-5-867_1
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Published: Ann Intern Med. 1972;76(5):867.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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