Robert M. Nalbandian, M.D.; Frank R. Camp Jr., M.S.; Nicholas F. Conte, M.D.; Keats K. Vining, F.A.C.P.
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Four new dithionite tests have recently been developed for the detection of hemoglobin S. One of these, the automated dithionite test, has been used in mass screening programs in metropolitan and miltary populations, constituting in aggregate a field test of more than 27 000 individuals. The automated technique processes 120 specimens per hour on ½ millilitre of anticoagulated whole blood at a reagent cost of 2 cents each. In Grand Rapids a comprehensive, mass screening program was undertaken successfully. The initial test population were the negro school children; the children who tested as positive identified the affected families in the
Nalbandian RM, Camp FR, Conte NF, et al. Use of Automated Dithionite Tests for Mass Screening for Hemoglobin S in Large Civilian and Military Populations.. Ann Intern Med. 1972;76:870. doi: https://doi.org/10.7326/0003-4819-76-5-870_3
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Published: Ann Intern Med. 1972;76(5):870.
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