Willibald Nagler, M.D., F.A.C.P.
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To define the nature of motor paralysis after an acute attack of intermittent porphyria, electrodiagnostic studies were performed in five patients. Fortnightly electromyographic studies, nerve-conduction velocity measurements, and biochemical tests were carried out from the acute onset of the paralysis to recovery. Nerve and muscle biopsies were performed in two patients. Ten to 14 days after the onset of the extensive paralysis an abundance of fibrillation potentials was found by needle electromyography. The appearance of polyphasic, large-amplitude, and long-duration potentials after 6 to 8 weeks was characteristic for neuronal regeneration. On each electromyographic examination, the coaxial needle electrode was inserted
Nagler W. Neuropathy in Acute Intermittent Porphyria.. Ann Intern Med. 1972;76:878. doi: https://doi.org/10.7326/0003-4819-76-5-878_4
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Published: Ann Intern Med. 1972;76(5):878.
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