Roger W. Kiser, M.D.; William J. deGroot, M.D.; E. R. McFadden Jr., M.D., F.A.C.P.
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Fourteen asthmatic subjects were studied during acute attacks of bronchospasm to determine when clinical manifestations of the disease would disappear in relation to the changes in pulmonary function. After base-line measurements were taken, each patient was given identical therapy, at hourly intervals, for a minimum of 5 hours, and serial observations were made. We recorded subjective complaints (dyspnea and wheezing) and objective findings (retraction and rhonchi) and correlated them with changes in physiology. Loss of subjective complaints occurred with one to three treatments, and the physiologic data improved as follows: airway resistance (RA), 43% change from baseline; specific conductance (SGa),
Kiser RW, deGroot WJ, McFadden ER. Acute Bronchial Asthma—Response to Treatment as Measured by Symptoms, Signs, and Pulmonary Function Studies.. Ann Intern Med. 1972;76:880. doi: 10.7326/0003-4819-76-5-880_1
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Published: Ann Intern Med. 1972;76(5):880.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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