S. WHITMORE, B.A.; H. CHIODI, PH.D., M.D.
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To the editor: It has been assumed that the pulmonary hyperventilation in many cirrhotic patients could be caused by an abnormal increase in the level of blood progesterone (1) but we could not find any measurements of plasma progesterone in cirrhotic patients in the literature. We have measured plasma levels in alcoholic cirrhotic patients with and without pulmonary hyperventilation to determine whether there are any correlations between plasma hormone levels and the degree of pulmonary hyperventilation*.
The subjects were 7 normal men and 25 male patients with laboratory and clinical diagnosis of alcoholic hepatic cirrhosis. None had clinical signs of
WHITMORE S, CHIODI H. Progesterone, Pulmonary Hyperventilation, and Cirrhosis. Ann Intern Med. ;77:326–327. doi: 10.7326/0003-4819-77-2-326_2
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Published: Ann Intern Med. 1972;77(2):326-327.
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