ALFRED BAKER, M.D.; MARSHALL KAPLAN, M.D.; HUBERT WOLFE, M.D.
A 59-year-old woman with ascites had clinical and laboratory evidence of myxedema with no history of congestive heart failure or renal disease. A liver biopsy specimen showed typical central congestive fibrosis. The pericentral hepatocytes were replaced by connective tissue. Liver biopsy blocks from two previously reported cases of myxedema ascites were obtained, and routine and special stains again showed typical central congestive fibrosis. The pathogenesis of this previously unrecognized finding in patients with myxedema ascites is unknown.
BAKER A, KAPLAN M, WOLFE H. Central Congestive Fibrosis of the Liver in Myxedema Ascites. Ann Intern Med. ;77:927–929. doi: 10.7326/0003-4819-77-6-927
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Published: Ann Intern Med. 1972;77(6):927-929.
Endocrine and Metabolism, Gastroenterology/Hepatology, Liver Disease, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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