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Thalassemia has come a long way since Whipple and Bradford first coined the term in 1936, from the Greek word for "sea" to emphasize the Mediterranean origin of affected individuals. Their term has since become a misnomer because the disorder occurs in high frequency among peoples far from the Mediterranean. Indeed medical provincialism has even raised its head with such terms as "British" or " Japanese" thalassemia to describe sporadic cases in populations with low frequency.
This second edition remains the standard reference on the subject. The opening chapters explain hemoglobin structure-function relationships lucidly and concisely. Even the busy practitioner
The Thalassaemia Syndromes.. Ann Intern Med. 1973;78:163. doi: 10.7326/0003-4819-78-1-163_1
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Published: Ann Intern Med. 1973;78(1):163.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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