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To the editor: Dr. Wilkins and her colleagues report (Ann Intern Med 77:930-932, 1972) a case of clinically apparent reinfection rubella in a naturally immune woman. Hankenes and Haram (1) reported a similar case in a gravid woman. Prior reports by Northrup (2) Strannegard (3), and Boué (4) stress the recurrence of clinical disease. Serologic evidence of reinfection after natural and vaccine-induced immunity has also been well documented (5, 6).
The significance of these findings on rubella-induced embryopathy is unclear. Rubella virus has been isolated from the products of conception of vaccinated women reinfected by wild-type virus during gestation (2),
TRAVERS H. Rubella Reinfection. Ann Intern Med. 1973;78:620–621. doi: https://doi.org/10.7326/0003-4819-78-4-620_3
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Published: Ann Intern Med. 1973;78(4):620-621.
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