Bernard M. Patten, M.D.; John Belizikian, M.D.; Lawrence Mallette, M.D.; Alan Prince, M.D.; Gerald Aurbach, M.D.; W. King Engel, M.D.
This content is PDF only. Please click on the PDF icon to access.
We report the first detailed study of the neurological, electromyographic, and muscle biopsy findings in patients with hyperparathyroidism.
Over 80% of our 16 patients presented with a distinct syndrome consisting of easy fatigability; weakness and atrophy of proximal muscles, particularly of the leg; tongue tremors; and normal or hyperactive reflexes. The presence or severity of weakness bore no relationship to the alteration of any serum ion measured, including calcium. The electromyograms showed short-duration, low-amplitude complex and, sometimes, polyphasic potentials mingled with high-amplitude, long-duration motor units. Motor and sensory nerve conduction times were normal. Muscle biopsies showed neurogenic atrophy of both
Patten BM, Belizikian J, Mallette L, Prince A, Aurbach G, Engel WK. Hyperparathyroid Neuromuscular Disease.. Ann Intern Med. 1973;78:815–816. doi: 10.7326/0003-4819-78-5-815_4
Download citation file:
Published: Ann Intern Med. 1973;78(5):815-816.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use