C. K. Bhatia, M.D.; J. Nidiry, M.D.; J. Harrell, M.D.; J. Mock, M.D.; S. H. Danovitch, M.D., F.A.C.P.
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We have assessed the efficacy and safety of selective splanchnic intra-arterial vasopressin infusion in controlling 28 episodes of torrential gastrointestinal hemorrhage in 21 patients. After localization of bleeding by endoscopy or splanchnic angiography, or both, appropriate arterial perfusion with 0.2 units of vasopressin per minute was undertaken. Cardiac function, serum electrolytes, osmolality, and urine output were closely monitored. If bleeding persisted after 4 to 6 hours of infusion, the rate was increased to 0.3 units of vasopressin per minute. Success was evidenced by clear nasogastric aspirates and stable clinical status and hematocrit values for 24 hours. Esophageal variceal and peptic
Bhatia CK, Nidiry J, Harrell J, et al. Selective Splanchnic Perfusion of Vasopressin in the Management of Torrential Gastrointestinal Hemorrhage.. Ann Intern Med. 1973;78:818. doi: 10.7326/0003-4819-78-5-818_3
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Published: Ann Intern Med. 1973;78(5):818.
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