Peter McPhedran, M.D.; Jack Weinstein, M.D.; Marshall G. Barnes, M.D.; Gloria Geloso, A.S.
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The detection of sickle-cell trait for the purpose of genetic counseling is important enough to justify mass screening programs. The detection of β-thalassemia trait is important both for genetic counseling and for the diagnosis of anemia, but detection methods have been too cumbersome for mass screening. We have previously shown that microcytosis identified by the Model S Coulter Counter (Coulter Electronics, Inc., Hialeah, Florida) is a useful clue to the diagnosis of β-thalassemia trait, and we have recently completed a large screening program for microcytosis. Between March 1971 and October 1972, 1000 patients (about 1% of those having blood counts
McPhedran P, Weinstein J, Barnes MG, et al. Mass Screening for the Detection of β-Thalassemia Trait.. Ann Intern Med. 1973;78:823. doi: 10.7326/0003-4819-78-5-823_3
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Published: Ann Intern Med. 1973;78(5):823.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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