Laura Slaughter, M.D.; James F. Morris, M.D.; Albert Starr, M.D.
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We reviewed the case records of 48 patients with infected prosthetic cardiac valves (out of 1236 patients who had valves implanted during 1960 to 1972). Survival rate with valvular infections was 40%. Our purpose of the study was to identify the factors that aided or decreased patient survival and to develop a program of treatment with antimicrobial agents. Several antimicrobics and various dosage schedules were used. Of 19 surviving patients, medical treatment alone was effective in 14, despite the continued presence of a valvular prosthesis. Reoperation was successful in five of nine patients. Continued chemoprophylactic or chemo-suppressive therapy was unnecessary
Slaughter L, Morris JF, Starr A. Prosthetic Valvular Endocarditis: A Twelve-Year Review.. Ann Intern Med. ;78:826. doi: 10.7326/0003-4819-78-5-826_4
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Published: Ann Intern Med. 1973;78(5):826.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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