Paul H. Levine, M.D., F.A.C.P.; Barbara R. Cho; Gregory C. O'Conor, M.D.; Costan W. Berard, M.D.; Vincent DeVita, M.D., F.A.C.P.; Paul Carbone, M.D., F.A.C.P.
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Burkitt's lymphoma, a lymphoreticular neoplasm with characteristic histological features, is of great interest to oncologists because of its unique geographical distribution and striking response to chemotherapy. The concentration of cases in areas of holoendemic malaria and time-space clustering have been cited as an indication of an infectious cause. Although one virus, the EpsteinBarr virus, has been closely associated with Burkitt's lymphoma because of the high antibody levels in patients with the lymphoma, it has not been possible to show a causative role for the virus.
The description of cases of Burkitt's lymphoma in the United States and other nonmalaria areas
Levine PH, Cho BR, O'Conor GC, et al. American Burkitt's Lymphoma: Current Status.. Ann Intern Med. 1973;78:831. doi: 10.7326/0003-4819-78-5-831_2
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Published: Ann Intern Med. 1973;78(5):831.
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