MICHAEL D. LOCKSHIN, M.D., F.A.C.P.
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To the editor: Recent publications about systemic lupus erythematosus in the ANNALS OF INTERNAL MEDICINE and elsewhere have emphasized aggressive forms of therapy for this disease (1, 2). Little emphasis has been placed on the need to fit therapy to the extent of clinical illness. In particular, little has been published about the
management of patients who have serologic findings compatible with the diagnosis of systemic lupus erythematosus but who do not have clinically evident multisystem disease.
I have seen six patients with serologically but not clinically diagnosable systemic lupus erythematosus since 1969, when the DNA-binding assay (3) was first
LOCKSHIN MD. Lupus Erythematosus, Treatment?. Ann Intern Med. ;78:969–970. doi: 10.7326/0003-4819-78-6-969
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Published: Ann Intern Med. 1973;78(6):969-970.
Lupus Erythematosus, Rheumatology.
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