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This subject is certainly topical at this time. The causes and effects of pyelonephritis are redefined, with increased awareness of its underlying anatomic relation to vesicoureteral reflux, and put into excellent perspective by the authors. They effectively destroy the magical, undefined characteristics of the disease and outline its treatment in a concise manner. Urologists have believed for years that some underlying anatomic mechanism caused pyelonephritis. The authors relate how urethral contamination in the female produces cystitis, which in turn results in renal parenchymal infection, but only when a pathway that allows upper tract contamination is present. This pathway is the
Vesicoureteral Reflux and Pyelonephritis.. Ann Intern Med. 1973;79:475–476. doi: https://doi.org/10.7326/0003-4819-79-3-475_3
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Published: Ann Intern Med. 1973;79(3):475-476.
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