DONALD G. VIDT, M.D.
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In this issue (pp. 511-517), Raja and associates raise the question, again, of the use of hyperosmolar dialysis solutions for peritoneal dialysis, by presenting an alternative to dextrose or sorbitol dialysate in selected clinical situations. The potentially hazardous complications of hyperglycemia, hypovolemia, hypernatremia, and hyperosmolar coma have been widely recognized and were emphasized in an earlier editorial in this journal (1). These complications and most of the solution-related deaths have been associated with 7% dextrose dialysate, used to facilitate volume reduction. The results of a workshop on the optimal choice of peritoneal dialysis solutions have been reported in a recent
VIDT DG. Hazards of Hyperosmolar Solutions. Ann Intern Med. 1973;79:599–600. doi: 10.7326/0003-4819-79-4-599
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Published: Ann Intern Med. 1973;79(4):599-600.
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