WILLIAM M. BLAYLOCK, M.D.; MARION WALLER, Ph.D.; DAVID E. NORMANSELL, Ph.D.
A patient with Sjögren's syndrome who developed hyperviscosity is described. A polyclonal increase in all immunoglobulins was present, and ultracentrifuge studies showed the presence of intermediate complexes. Very high titers of rheumatoid factors were present. The detailed course of treatment for a 1-year period is presented and correlated with clinical and laboratory variables, such as serum viscosity, protein electrophoresis, levels of gamma globulin, rheumatoid factors, and ultracentrifuge patterns. The remarkable recovery of this patient after a 3-year period is documented.
BLAYLOCK WM, WALLER M, NORMANSELL DE. Sjögren's Syndrome: Hyperviscosity and Intermediate Complexes. Ann Intern Med. 1974;80:27–34. doi: 10.7326/0003-4819-80-1-27
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Published: Ann Intern Med. 1974;80(1):27-34.
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