ROY T. STEIGBIGEL, M.D.
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To the editor: The recent review of cephaloridine by Dr. G. L. Mandell (Ann Intern Med 79:561-565, 1973) discusses the probable lack of effectiveness of cephalothin in the treatment of bacterial meningitis. However, two reports (1, 2) are cited in which pneumococcal meningitis is successfully treated with cephaloridine. It should be emphasized that in both of these reports cephaloridine was administered intrathecally to all patients, either daily or on alternate days for at least 1 week. In evaluating cephaloridine for the treatment of pneumococcal meningitis we should consider that intrathecal treatment was used in these studies, which is a route
STEIGBIGEL RT. Cephaloridine. Ann Intern Med. ;80:277. doi: 10.7326/0003-4819-80-2-277_1
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Published: Ann Intern Med. 1974;80(2):277.
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